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Fluorescence microscopy of islets in the omentum transplanted within the biologic scaffold. Shown in red (insulin staining) and blue (DAPI nuclear staining).

Research Findings Show Tissue-Engineered Islet Transplant Achieves Insulin Independence

Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have produced the first clinical results demonstrating that pancreatic islet cells transplanted within a tissue-engineered platform can successfully engraft and achieve insulin independence in type 1 diabetes. The findings were published in the May 11 issue of the New England Journal of Medicine.

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Lina Shehadeh, Ph.D.

Aptamers May Hold Clue to Treating Heart Failure

As the heart progresses toward heart failure, it produces high levels of a protein called Osteopontin, which is known to activate pathological remodeling of the heart. Lina Shehadeh, Ph.D., assistant professor of medicine, and a team of investigators decided to see if they could find a way to block Osteopontin signaling to prevent — or possibly even reverse — heart failure.

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Amar R. Deshpande, M.D.

Next-Generation Medical Education Task Force to Design the Ideal Training for Doctors of the Future

As medicine and the delivery of health care continue to be transformed, the University of Miami Miller School of Medicine — already a national leader in innovative education — is taking a global look at transforming the entire medical curriculum. And Amar R. Deshpande, M.D., who is leading the charge as chair of the Next Generation Medical Education Task Force, says the timing couldn’t be better.

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