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BC-3 cells were stained with DAPI, anti-vFLIP, anti-CADM1, and cholera toxin B conjugated with red fluorescence to detect GM-1 and subjected to confocal microscopy.

Sylvester Researchers Identify Protein that Triggers Virus-Mediated Chronic Inflammation and Cancers

Viruses are linked to approximately 12 percent of all cancers and are associated with chronic inflammation. Sylvester Comprehensive Cancer Center researchers Noula Shembade, Ph.D., Richard Hunte and colleagues honed in on what activates that process. They found the human protein CADM1 interacts with Kaposi’s sarcoma viral proteins and promotes inflammation that can result in development of certain cancers.

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Miller School of Medicine Rises in NIH Research Grant Funding

The Miller School of Medicine received $120.7 million in research grants from the National Institutes of Health in Federal Fiscal Year 2017 — a $9.5 million increase over the school’s FFY 2016 total. According to the national rankings of medical schools based on data compiled by the Blue Ridge Institute for Medical Research, that total made the Miller School the No. 1 NIH-funded institution in Florida.

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Sylvester Researchers Discover New Pathway Linking Inflammation and Cancer

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, collaborating with outside investigators, has discovered a new pathway of inflammation-driven cancer development. Their findings, “Initiation of Inflammatory Tumorigenesis by CTLA4 Insufficiency Due to Type 2 Cytokines,” were published online on January 26 by the Journal of Experimental Medicine.

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